NOT a diagnosis but a description of symptoms that may indicate disease of the upper GI tract

Aetiology

Organic causes (25%)

• GORD
• Peptic ulcer disease
• Drugs (especially NSAIDs and COX2 inhibitors)
• Gastric cancer

Functional dyspepsia (75%)

• No evidence of culprit structural disease
• Associated with other functional gut disorders e.g. IBS

Clinical features

Rome III criteria

• Epigastric pain/burning
• Postprandial fullness
• Early satiety

Signs

• If uncomplicated - epigastric tenderness only
• If complicated - cachexia, mass, evidence of gastric outflow obstruction, peritonism

Investigations + management

If no alarm symptoms and < 60