Normal embryo that is implanted outwith the endometrial cavity

Aetiology

Risk factors

• Previous ectopic
• Tubal damange - infection, endometriosis, surgery
• IUD
• Smoking
• Infertility
• Infertility treatment
• Extremes of reproductive age

Pathophysiology

• Fallopian tube is the most common site
• Other sites: ovary, peritoneum, other organs (e.g. liver, cervix, C-section scar)
• Pregnancy of unknown location is halfway diagnosis if no pregnancy is located on US

Clinical features

• Consider diagnosis in any female of reproductive age with amenorrhoea and acute hypotension or an acute abdomen

Symptoms

• Pain, shoulder tip pain
• Bleeding
• Collapse