Non-bacterial thrombotic endocarditis

• Multiple small, sterile vegetations which do not destroy valves
• Can cause embolic disease
• Usually occurs during a hypercoagulable state e.g. pregnancy, cancer

Libmen-Sacks endocarditis

• Small sterile emboli, often under the surfaces of the valves or on the chords
• Occurs more often in patients with lupus
• Thought to be due to the deposition of immune complexes